Approach of nanostructured lipid carriers (NLCS): tool as a new targeted drug delivery system: A review
1 Department of Pharmaceutics, Assistant Professor, School of Pharmaceutical Education and Research, Berhampur University, Odisha,760007, India.
2 Aurosri Institute of Pharmaceutical Education and Research, Kadai Tangi, Cuttack,754022 Odisha, India.
3 Department of Pharmaceutics, Assistant Professor, School of Pharmaceutical Education and Research, Berhampur University, Odisha,760007, India.
4 Department of Pharmaceutics, Professor, School of Pharmaceutical Education and Research, Berhampur University, Odisha,760007, India.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 19(03), 184–193.
Article DOI: 10.30574/wjbphs.2024.19.3.0594
Publication history:
Received on 29 July 2024; revised on 07 September 2024; accepted on 09 September 2024
Abstract:
The most significant advancement in the creation of more efficient medicine delivery systems has come from nanotechnology. The target drug delivery system is now incredibly simple and efficient thanks to cutting-edge nanotechnology. A target drug delivery system is a technique for getting the medication's active ingredient to the body's injured area. Nanostructured lipid carriers (NLC) are an exceptional and unique development in the field of nanotechnology. Site-specific drug delivery systems can be constructed using NLCs, a novel form of second generation emulsion system that combines spatially incompatible liquid lipids with a mixture of solid lipids. This potential delivery mechanism provides longer stability than SLNs. Because of the potential advantages of drug design at the nanoscale, such as the capacity to increase immunogenicity and bioavailability, which can lead to the development of more convenient administration routes, fewer side effects, improved biodistribution, and an extended drug life cycle, the application of nanostructured and nanophases is seen to bridge the gap between biological and physical sciences.
Keywords:
Nanostructured; Nanostructured lipid Carriers (NLCs); Homogenization; Microemulsion; Emulsification
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