To assess the impact of covid-19 on maintenance haemodialysis patients: A retrospective study in a tertiary care hospital in south Kerala

NIHAL MUHAMMED 1, LEKSHMI R 1, PRAVEENA R PRASAD 1, CHINTHA CHANDRAN 2, * and SHAIJU S DHARAN 3

1 Pharm D Intern, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Trivandrum, Kerala, India.
2 Assistant Professor, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Trivandrum, Kerala, India.
3 Principal/HOD, Departement of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Trivandrum, Kerala, India.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(01), 293–304.
Article DOI: 10.30574/wjbphs.2024.18.1.0202
 
Publication history: 
Received on 07March 2024; revised on 14 April 2024; accepted on 16 April 2024
 
Abstract: 
COVID-19 was started as a global pandemic in March 2020. It is an infectious disease caused by the SARS COV-2 virus and it has affected the care and outcomes of patient treated with dialysis. Patients with CKD could be more vulnerable to a severe form of COVID-19. Higher risk of mortality caused by COVID-19 in haemodialysis patient is detected with older age, comorbidities and impaired immune response. Clinical presentation of COVID-19 on haemodialysis patient is fluctuating from asymptomatic or mild disease to severe life threatening illness. Initially, common symptoms were presented including fever, dry cough, fatigue, diarrhea and dyspnea. On computerized tomography scan patients had shown bilateral ground-glass opacities revealing that COVID-19 predominantly affected the respiratory system. Maintenance haemodialysis is the most widely used treatment for end stage CKD patients and it has the higher risk of initial mortality from coronavirus 2019. CKD is a severe medical entity with a higher prevalence of comorbid conditions, mostly including diabetes, hypertension, disproportionally affecting older adults. The aim of this study is to assess the impact of COVID-19 on maintenance haemodialysis patient and the objective of the study is to assess the mortality of COVID-19 on maintenance haemodialysis patient and risk factors associated with it and also the severity of COVID19 on maintenance haemodialysis patient. We performed a retrospective cross sectional study using 39 samples. The samples were collected from the case files of the patients who fulfill the inclusion criteria and then the collected data was statistically interpreted using SPSS software version 22.0 and then the severity and mortality of the COVID-19 on maintenance haemodialysis patient was analyzed. The final analysis included 39 patient who met the inclusion criteria .Here the incidence of COVID-19 on maintenance haemodialysis patient is more prone on 41-60 years of age.
 
Keywords: 
Haemodialysis; COVID-19; Severity; Risk factors; Mortality; Vaccination.
 
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