Assessment of consumption of kolanut (Cola nitida) on hepato-renal and reproductive hormones biomarkers among chronic consumers in Aritallin Bayelsa State Nigeria

Kolanut is a caffeine containing nut. This study was aimed at assessment of consumption of kolanut (Colanitida) on hepato-renal and reproductive hormones biomarkers among chronic consumers in Aritallin, Bayelsa State, Nigeria. Five millilitres blood specimen was withdrawn for biochemical investigations from each of the sixty apparently healthy volunteers with thirty being chronic consumers (≥ 5) years of kolanut (Cola nitida) while the other thirty being non kolanut consumers. The results revealed significant elevation (p<0.05) of alanine aminotransferase (21.41 ± 2.83) U/I, aspartate aminotransferase (18.75 ± 2.07) U/I, alkaline phosphatise (32.60 ± 2.18) U/I, creatinine (137.22 ± 9.78) µmol-1 and urea (15.92 ± 2.82) mmol-1 in the chronic consumers as compared to the non consumers alanine aminotransferase (10.50 ± 1.40) U/I, aspartate aminotransferase (9.60 ± 1.22) U/I, alkaline phosphatise (18.67 ± 1.78) U/I, creatinine (66.30 ± 1.86) µmol-1 and urea (5.22 ± 1.31) mmol-1 . However, there was no significant differences (p>0.05) between the chronic consumers and non consumers of kolanut (Colanitida) in the measured reproductive hormones. In conclusion, chronic consumption (≥5 years) of kolanut (Cola nitida) may influence hepato-renal disorders.