A case report on Azathioprine induced hepatotoxicity
1 Pharm D Intern, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India.
2 Associate Professor, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India.
3 Principal/ HOD, Ezhuthachan college of pharmaceutical sciences, Marayamuttom, Thiruvananthapuram, Kerala, India.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 14(03), 355–358.
Article DOI: 10.30574/wjbphs.2023.14.3.0270
Publication history:
Received on 08 May 2023; revised on 23 June 2023; accepted on 26 June 2023
Abstract:
The most frequent cause of acute liver failure is drug induced liver damage. The lack of diagnostic testes or biomarkers, identification of DILI is difficult one. In most cases DILI was mild and reversible. Azathioprine, is a widely used immunosupressive agent had a nature of causing liver injury but rare. It basically presents with mild symptoms. Azathioprine can cause idiosyncratic liver injury, usually presented with juandice and fatigue and then linked to elevated liver enzymes. It is reversible and typically resolveson cessation of Azathioprine. This case focuses on Azathioprine’s nature of hepatotoxicity. After the withdrawal of offending agent, it is resolved.
Keywords:
DILI; Azathioprine; Corticosteroid; Hepatotoxicity
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0