Case Report: An interesting case of a patient who presented with increasing thirst and polyuria in a district general hospital in the UK
1 Department of Diabetes and Endocrinology, Royal Albert Edward Infirmary, Wigan, WN1 2NN (UK).
2 Royal Albert Edward Infirmary, Wigan, WN1 2NN (UK).
Review
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(03), 052–056.
Article DOI: 10.30574/wjbphs.2023.13.3.0114
Publication history:
Received on 21 January 2023; revised on 01 March 2023; accepted on 03 March 2023
Abstract:
A gentleman presented with polyuria and polydipsia to the Endocrine Clinic in late 2020. The patient was investigated extensively. Diabetes Mellitus was excluded, and the patient was investigated for Diabetes Insipidus (DI). The patient was passing more than 3L of urine/day. A Water deprivation Test (WDT) was done, and it suggested Partial Central Diabetes Insipidus (Partial Arginine Vasopressin Deficiency), which is a rare disorder. Various blood tests looking for the aetiologies such as Sarcoid, Germinoma, IgG4 Disease and Vasculitis were negative. MRI scan of the Pituitary carried out twice showed no abnormality. The patient’s distressing symptoms were alleviated with proper treatment (nasal Desmopressin). Thus, it is important to diagnose this treatable condition which is often confused with Primary Polydipsia. The patient has since then been clinically and biochemically well.
Keywords:
Polyuria; Polydipsia; AVP; Diabetes Insipidus; Pituitary
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0