Case report of permethrin induced exfoliative dermatitis

RamyaBalaprabha G 1 *, Rama Rao T 2, Sri Vaishnavi P 3, Harika Guptha M 3 and Krishna Sree N 3

1 Department of Pharm. D, CMR College of Pharmacy, Kandlakoya (V), Medchal Road, Hyderabad, Telangana – 501401.
2 Department of M. Pharm., Ph. D, CMR College of Pharmacy, Kandlakoya (V), Medchal Road, Hyderabad, Telangana – 501401.
3 Department of Pharm. D, CMR College of Pharmacy, Kandlakoya (V), Medchal Road, Hyderabad, Telangana – 501401.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 16(03), 055–057
Article DOI: 10.30574/wjbphs.2023.16.3.0495

 

Publication history: 
Received on 20 October 2023; revised on 03 December 2023; accepted on 05 December 2023
 
Abstract: 
Exfoliative dermatitis is a life threatening condition associated with erythema and scaling that requires proper diagnosis, identification of underlying etiology, and management. Male to female preference for erythroderma ranges from 2 to 4 to 1, with a mean onset age of 40 to 60.Exfoliative dermatitis may be brought on by a medication reaction or an underlying cancer, however the exact cause is unknown. We  presented a 45-year-old female patient with Exfoliative dermatitis who admitted to the hospital with complaints of dark colored itchy lesions all over the body for last 1 month, itching over back, axilla and chest region, fever due to application of permethrin lotion. The most common cause of exfoliative dermatitis is permethrin lotion. The drug must be stopped and proper treatment must be given like anti histamines, corticosteroids, topical emollients. Early diagnosis and early discontinuation of the drug significantly reduces mortality.
 
Keywords: 
Exfoliative Dermatitis; Erythema; Emollients; Lesions; Erythoderma; Corticosteroids.
 
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