Chronic kidney disease associated with hypertension
1 Department of Nephrology, First affiliated hospital of Xinjiang Medical University, China.
2 Department of General Surgery, DHQ hospital Hunza, Pakistan.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 16(03), 194–199.
Article DOI: 10.30574/wjbphs.2023.16.3.0509
Publication history:
Received on 05 November 2023; revised on 20 December 2023; accepted on 23 December 2023
Abstract:
Background: Globally, chronic kidney disease (CKD) is acknowledged as a major public health issue. Both the incidence and prevalence of chronic kidney disease (CKD) are rising with immense pace worldwide. Hypertension and diabetes mellitus is the main risk factor of chronic kidney disease.
Objective: To determine chronic Kidney disease associated with hypertension
Methods: A cross-sectional study was conducted at district headquarter hospital, Mianwali, Pakistan, which was performed between June 2020 and February 2022, the total number of patients in our study were 120. The number of Male patients were 49 and female were 71. In 120 consecutive patients who underwent for blood tests and Blood pressure monitoring. We also took stages of chronic kidney disease (CKD stage 1,2,3A,3B,4 and 5). We did renal function test for all patients (serum creatinine and serum urea). Data was tabulated and analyzed by SPSS.
Results: In a current study total 120 patients were enrolled. The minimum age of patients were30 and the maximum age of the patients were 84. The mean age were 50.60±10.9 years. The minimum systolic blood pressure were 130 and maximum systolic blood pressure were 200. The mean systolic blood pressure were 149.55±13.5.
The minimum diastolic blood pressure were 80 and the maximum diastolic blood pressure were 100. The mean diastolic blood pressure were 89.57±3.76
The frequency of male patients were 49 and its percentage were 40.8. The frequency of female patients were 71 and its percentage were 59.2. The frequency of age group 30-50 years were 61 and its percentage were 50.8. The frequency of age group 51-70 years were 52 and its percentage were 43.3. The frequency of age group >70 years were 7 and its percentage were 5.8. The mean of renal functional test Serum creatinine were 7.82 mg/dl and its SD value were 3.59 mg/dl. The mean of renal functional test Serum urea were 109.90 mg/dl and its SD value were 24.30 mg/dl.
· The mean glomerular filtration rate were 20.36 ml/min and its SD value were 13.2 ml/min.
· The mean weight of patients were 56.61 kg and its SD value were 10.19 kg.
· The P-value of stages of Chronic kidney disease (CKD) were 0.133. The P-value of hypertension were 0.074.
Conclusion: Hypertension and diabetes mellitus is the main cause of Chronic kidney disease (CKD). Stage 5 Chronic kidney disease (CKD) patients were more in our study as compare to other stages of CKD. We concluded in our study that after age of 30, patients have higher risk of Chronic kidney disease (CKD).
Keywords:
Chronic kidney disease (CKD); Hypertension; Diabetes Mellitus
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