School of Medicine and Dentistry, University of Ghana, Accra.
World Journal of Biology Pharmacy and Health Sciences, 2025, 22(02), 378–388
Article DOI: 10.30574/wjbphs.2025.22.2.0502
Received on 16 April 2025; revised on 27 May 2025; accepted on 29 May 2025
The CRISPR-Cas9 system has revolutionized the field of genetic engineering by offering a precise, efficient, and cost-effective method for editing genomes. This document explores the mechanism of CRISPR-Cas9, detailing its origins, molecular functionality, and the wide array of its applications in biotechnology, medicine, and agriculture. It highlights key advancements in gene therapy, functional genomics, and the development of genetically modified organisms. The paper also discusses the ethical and regulatory concerns associated with genome editing, emphasizing the need for responsible use of this transformative technology. The aim is to provide a comprehensive overview of how CRISPR-Cas9 is shaping the future of genetic research and therapy.
CRISPR-Cas9; Genome Editing; Gene Therapy; Biotechnology; Genetic Engineering; Molecular Biology; Disease Treatment; Functional Genomics; Ethical Considerations
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Andrew Tetteh Mensah. CRISPR-Cas9 applications in pharmaceutical biotechnology: Therapeutic potentials and ethical implications. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(02), 378–388. Article DOI: https://doi.org/10.30574/wjbphs.2025.22.2.0502.