Delving into artemisinin’s shadow: Insights from a unique case of artesunate – resistant complicated falciparum malaria

Puchakayala Sai Poojitha *, Bhimasen Soren and Kanugula Sudheer

Department of General Medicine, Great Eastern Medical school and Hospital, Srikakulam, Andhra Pradesh, India.
 
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(01), 408–412.
Article DOI: 10.30574/wjbphs.2024.18.1.0220
Publication history: 
Received on 14 March 2024; revised on 24 April 2024; accepted on 26 April 2024
 
Abstract: 
The emergence of drug-resistant malaria poses a formidable health challenge in emerging nations such as India. The ineffectiveness of the medicine artemisinin, which is essential for treating malaria, will quickly undermine the treatment and outlook for malaria patients. If, following a complete course of therapy with Artesunate Combination Therapy and without any instances of vomiting or diarrhoea, there is no clinical or parasitological improvement in the patient within 72 hours, resistance may be considered. Reports of artemisinin-resistant Plasmodium falciparum malaria are rare in the southern regions of India. This article details a case of rare Artesunate-resistant complex falciparum malaria.
 
Keywords: 
Artesunate Resistant Malaria; Complicated Malaria; Artemisinin compounds; Artemisinin combination therapy; Falciparum Malaria
 
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