Development and estimation of an oro-dispersible anti-malarial dosage form for pediatric patient

POOJA YADAV; RAMAKANT SHARMA; SHABNAM KHAN; JEEVAN PATEL and RAKESH PATEL

doi:10.30574/wjbphs.2023.13.1.0029

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Development and estimation of an oro-dispersible anti-malarial dosage form for pediatric patient

POOJA YADAV ^*, RAMAKANT SHARMA, SHABNAM KHAN, JEEVAN PATEL and RAKESH PATEL

School of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore, India.

Research Article

World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 250-257.

Article DOI: 10.30574/wjbphs.2023.13.1.0029

DOI url: https://doi.org/10.30574/wjbphs.2023.13.1.0029

Publication history

Received on 03 December 2022; revised on 11 January 2023; accepted on 14 January 2023

Abstract

Artemether-Lumefantrine tablets are inconvenient for caregivers to administer as they need to be crushed and mixed with water or food for infants and young children. Further, in common with other anti-malarial, they have a bitter taste, which may result in children spitting the medicine out and not receiving the full therapeutic dose. There was a clear unmet medical need for a formulation of AL specifically designed for children.

Keywords

Oro-dispersible; Pediatric; Artemisinin; Lumefantrine; Malaria

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How to cite this article

POOJA YADAV, RAMAKANT SHARMA, SHABNAM KHAN, JEEVAN PATEL and RAKESH PATEL. Development and estimation of an oro-dispersible anti-malarial dosage form for pediatric patient. World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 250-257. Article DOI: https://doi.org/10.30574/wjbphs.2023.13.1.0029