Early detection of lung adenocarcinoma on CT scan
Department of Radiology, The First Affiliated Hospital of Xinjiang Medical University, Xinyi Road, Urumqi, Xinjiang, PR China.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(02), 251–259.
Article DOI: 10.30574/wjbphs.2024.18.2.0278
Publication history:
Received on 31 March 2024; revised on 10 May 2024; accepted on 13 May 2024
Abstract:
Background: Lung cancer is the most common human malignancy and the principal cause of cancer-related death worldwide. Nowadays, adenocarcinoma is the most common histologic form, making up over half of all cases
Objective: To determine the early detection of lung adenocarcinoma on CT scan
Methods: A cross-sectional study was conducted at Jinnah Hospital Lahore Pakistan, which was performed between September 2020 to October 2023, The name of CT scan machine which was used in our study was Toshiba 64 slice and its slice thickness was 0.5 mm. Iodine based contrast is used. The total number of patients in our study were 150. The number of Male patients were 61 and female were 89. For all patients, we did diagnostic tests CT test . BMI parameter of every patients we took. We also took detailed history from the patients about the signs and symptoms. We did both the Lung window and the Mediastinal window. Data was tabulated and analyzed by SPSS version 26.
Result: In a current study total 150 patients were enrolled. The minimum age of patients were 43 years and the maximum age of the patients were 77 years. The mean age were 59.60±7.877 years.
The minimum BMI of patients were 26 (Kg/m2) and the maximum BMI were 34 (Kg/m2). The mean BMI were 28.55±3.740 (Kg/m2). The minimum size of the Lung Adenocarcinoma of patients were 0.3 cm and the maximum size of Lung Adenocarcinoma of patients were 2.8 cm. The mean size of the lung adenocarcinoma were 1.413±0.627 cm.
The stage of lung adenocarcinoma in the age group of 41-50 years 1A1 were 8, 1A2 were 7 and 1A3 were 2 . The total patients with age 41-50 years were 17. The stage of lung adenocarcinoma in the age group of 51-65 years 1A1 were 34, 1A2 were 47 and 1A3 were 19. The total patients with age 51-65 years were 99. The stage of lung adenocarcinoma in the age group of >66 years 1A1 were 6, 1A2 were 11 and 1A3 were 17. The total patients with age >66 years were 34.
P-value of stages of lung adenocarcinoma in age group was 0.03.
The stage of lung adenocarcinoma 1A1 in male patients were 17 and female were 31. The stage of lung adenocarcinoma 1A2 in male patients were 28 and female were 36. The stage of lung adenocarcinoma 1A3 in male patients were 16 and female were 22. Total male patients were 61 and females were 89.P-value of stages of lung adenocarcinoma in gender was 0.04.
Conclusion: We concluded that routine CT examination could detect more lung cancer at an early stage, especially adenocarcinoma, and detect patients with less aggressive features. The main advantage of the CT scan is, its non-invasive, painless diagnostic test as compared to biopsies. The chance of spreading of cancer cell is reduced. In our study females were more as compared to males.
Keywords:
Low-dose CT (LDCT); Tumour-node-metastasis (TNM); Computed Tomography (CT); Lung squamous-cell carcinoma (SCC); Positron emission tomography (PET).
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