Evaluation of antimicrobial potential and phytochemical screening of Moringa oleifera leave extract: An Emerging folkloric medicinal plant in Maiduguri, Borno state, Nigeria

Fatima Adamu Lawan 1, *, Binta Baba Shehu 2, Ali Abba Gana Benisheikh 3, Abba Mohammad Dige 4, Hassan Arabi Jidda 5 and Abdullahi Abdulkadir 6

1 Department of Veterinary Microbiology, Faculty of Veterinary Medicine, University of Maiduguri, Nigeria
2 Department of Biochemistry, Faculty of Sciences, University of Maiduguri, Borno state, Nigeria
3 Department of Applied Microbiology and Biotechnology, Faculty of Science and Engineering, University of Wolverhampton, United Kingdom/  Centre for Biotechnology, University of Maiduguri, Borno state, Nigeria
4 North East Zonal Biotechnology Centre of Excellence, University of Maiduguri, Borno state, Nigeria
5 Department of Microbiology, Faculty of Science, University of Maiduguri, Borno state, Nigeria
6 Department of Biological Sciences, Faculty of Science, University of Maiduguri, Borno State, Nigeria
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2020, 04(03), 043-047.
Article DOI: 10.30574/wjbphs.2020.4.3.0096
Publication history: 
Received on 18 November 2020; revised on 30 November 2020; accepted on 02 December 2020
 
Abstract: 
The aim of this study was to evaluate the antimicrobial potential and phytochemical screening of Moringa oleifera leave extract as folkloric medicinal alternative. The phytochemical screening result revealed the presence of Alkanoids, Saponins, Fats & oil, Terpenoids and Tanin in all the solvents used for the study. Agar-disc diffusion method were used to determine the antimicrobial activities of the Moringa oleifera extracts on microorganisms. Maximum activities of inhibition were recorded on Ethyl acetate (50mg/ml) against Pseudomonas auroginusa, moderarate activities against Escherichia coli. Likewise 50mg/ml of Haxane extract show weak activities on Pseudomonas aeruginosa, moderate in both Staphalococcus aureus and Escherichia coli. Whereas 50mg/ml of Methanol show moderate activity on Pseudomonas aeruginosa, Staphalococcus aureus and weak activities on Escherichia coli respectively. The research revealed that Moringa oleifera bioactive components would be a safer alternative for curative and preventive emerging folkloric medicinal plant for treatment of bacterial ailments in Maiduguri, Borno state, Nigeria.
 
Keywords: 
Phytochemical Screening; Antimicrobial Potential; Moringa oleifera; An Emerging Folkloric; Medicinal Plant; Maiduguri; Borno State.
 
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