Evaluation of the antioxidant activity of certain extracts from the leaves of Phlomis crinita Cav from North western Algeria
Faculty of Pharmacy, University of Algiers 1, Algiers, Algeria.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 16(02), 025–028.
Article DOI: 10.30574/wjbphs.2023.16.2.0443
Publication history:
Received on 07 September 2023; revised on 27 October 2023; accepted on 30 October 2023
Abstract:
The Phlomis crinita Cav., a widely distributed Lamiaceae in northwestern Algeria, possesses numerous therapeutic virtues. The objective of this study is to evaluate the antioxidant properties of the leaves of this species by comparing them to ascorbic acid using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method.
The assessment of antioxidant properties of extracts obtained through reflux, including chloroform, n-butanol, and ethyl acetate, revealed a highly significant activity with IC50 values comparable to that of ascorbic acid (reference), especially for the chloroform extract. These results may be attributed to polyphenols, particularly tannins and flavonoids. It would be interesting to quantify them and determine if there is a correlation between their content and the intensity of this activity.
Keywords:
Phlomis crinita Cav; Antioxidant activity; DPPH; Polyphenols; Tannins; Flavonoids
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0