Exercise regulating mechanism for plasticity of aging hippocampus
1 School of Life Sciences (Neuroscience), University of Warwick, Coventry, United Kingdom.
2 Department of Orthopedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
3 Department of Orthopedics, Ipswich Hospital, Heath Rd, Ipswich IP4 5PD, United Kingdom.
4 Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
5 Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 19(02), 332–339.
Article DOI: 10.30574/wjbphs.2024.19.2.0500
Publication history:
Received on 02 January 2024, revised on 14 June 2024, and accepted on 03 August 2024
Abstract:
There are a number of characteristics responsible for the loss of vascular as well as metabolic integrity which is associated with the aging progression. These vascular and metabolic integrity losses instigate comprehensive damage in regional, biomarker, and functional areas. Instead, Exercise plays a dynamic role in sustaining a healthy body, consequently support to uphold healthy vascular and cellular integrity to maintain a healthy brain. Although the human brain shrinks with increasing age, reports have hinted that the brain is likewise capable of significant plasticity in individuals with progressive age. In this review, the prospective benefits of exercise that have the ability to modulate the plasticity of the aging brain, particularly the hippocampus will be discussed. This review will further elaborate on how these exercises modulate the plasticity of the aging hippocampus based on previous and current reports.
Keywords:
Exercise; Astrocyte; Microglia; Neuroinflammation; Autophagy; Mitochondria; Aging hippocampus; Neuroplasticity
Full text article in PDF:
Copyright information:
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0