Floating drug delivery systems: A review
Department of Pharmaceutics, Samarth Institute of Pharmacy, Belhe, Pune 412410, Maharashtra, India.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(02), 065–073.
Article DOI: 10.30574/wjbphs.2024.18.2.0249
Publication history:
Received on 17 March 2024; revised on 30 April 2024; accepted on 02 May 2024
Abstract:
To boost medication bioavailability, target the stomach mucosa, and lengthen gastric residence time, a multi-unit oral floating drug delivery system was created. Due to their potential to enhance drug delivery, floating tablets have become more significant in pharmaceutical formulation. In the upper GIT, where the environment is acidic, tablets absorbs poorly. The bioavailability shows 50% when administer orally. An H2-receptor antagonist called tablets is frequently prescribed to treat gastrointestinal issues brought on by excess stomach acid. With the right excipients and polymers, floating tablets are meant to float on the contents of stomach Over an extended length of time, extending medication release and bioavailability. This review examines the advantages, disadvantages, and in vitro or in-vivo evaluation of famotidine floating tablets with an emphasis on their potential to improve treatment outcomes and patient compliance.
Keywords:
Bioavailability; Formulation; Resistance; Floating
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0