Formulation and evaluation of herbal nanosuspension of Scoparia dulcis
1 Department of pharmaceutics, Al Shifa College of Pharmacy, Poonthavanam PO, Perinthalmanna, Kerala, India- 679325.
2 Al Shifa College of Pharmacy, Poonthavanam PO, Perinthalmanna, Kerala, India- 679325.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 339-343.
Article DOI: 10.30574/wjbphs.2023.13.1.0055
Publication history:
Received on 16 December 2022; revised on 19 January 2023; accepted on 22 January 2023
Abstract:
Background: The aim of this study is to formulate nanosuspension of Scoparia dulcis. This plant species is mainly used as an analgesic, antipyretic, and urinary issues as well as stomach disorders, kidney stones, hypertension, diabetes, and inflammation. In this study alcoholic extracts of Scoparia dulcis are used. The ionic gelation method is the most suitable method to formulate polyherbal nanosuspension.
Methods: Herbal nanosuspension was prepared by the emulsion ionic gelation method. Chitosan (CS) is a polymer, and Sodium tripolyphosphate (STPP) is an inorganic compound. Polyethylene glycol (PEG) is used as a stabilizer.
Result: The herbal nanosuspension formulations were evaluated for pH, viscosity, and stability.
Conclusion: Using optimal nanoparticles herbal nanosuspension is formulated. The F4 formulation has proper viscosity and stability.
Keywords:
Scoparia dulcis; Herbal nanosuspension; Ionic gelation method; Chitosan; Polyethylene glycol
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