1 Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.
2 Department of Pharmaceutical Chemistry, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-414502.
3 Department of Quality Assurance Techniques, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412105.
World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 016–020
Article DOI: 10.30574/wjbphs.2025.22.3.0399
Received on 28 February 2025; revised on 09 April 2025; accepted on 12 April 2025
Globally five to ten percent of women who are of reproductive age suffer from Polycystic Ovary Disease, a complicated endocrine disease marked by irregular menstrual periods, hyperandrogenism, and polycystic ovarian morphology. We explore the significance of insulin resistance, metabolic syndrome, and psychosocial comorbidities in addition to talking about the genetic, hormonal, and environmental variables that contribute to PCOD. The most recent diagnostic standards, such as the Rotterdam criteria, are examined, and various forms of treatment including lifestyle changes, medications, and surgery are assessed critical. Emphasis is placed on recent developments in our knowledge of the molecular mechanism behind PCOD and new treatment targets
Polycystic Ovarian Disease; Androgen; Follicular Maturation; Insulin resistance; Diagnostic tools
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Saba Shahjahan Inamdar, Prajkta Annasaheb and Sanket Pandurang Shinde. Genetic and epigenetic factors contributing to the development of PCOD. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 016–020. Article DOI: https://doi.org/10.30574/wjbphs.2025.22.3.0399.