Is H3N2 Influenza flare-up and troubling like COVID?

Raghavendra Rao M.V 1, *, Hitesh Lakshmi Billa 2, A. Rekha 3, Sireesha Bala 4, Mahendra Verma 5, M. M. Karindas 6, Ilie Vasiliev 7, Mallem Dinakar 8 and Chennamchetty Vijay Kumar 9

1 Scientist-Emeritus, Director research, Apollo Institute of Medical Science and Research, Hyderabad, TS, India
2 Department of Interventional Pulmonology, Apollo Institute of Medical Science and Research, Hyderabad, TS, India.
3 Department of Surgery and Dean, Apollo Institute of Medical Sciences and Research, Jubilee Hills, Hyderabad, Telangana, India.
4 Department of Pharmacology, Dean of Basic Medical sciences, Avalon University school of Medicine, Curacao.
5 American University School of medicine, Aruba, Caribbean Islands.
6 Department of Oncology, world Academy of Medical sciences, Netherlands.
7 Department of Internal Medicine, world Academy of Medical sciences, Netherlands.
8 Department of forensic Medicine, Apollo Institute of Medical, Sciences and Research, Jubilee Hills, Hyderabad, Telangana, India.
9 Department of Pulmonary Medicine, Apollo Institute of Medical Science and Research, Hyderabad, TS, India.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2023, 14(01), 020–030.
Article DOI: 10.30574/wjbphs.2023.14.1.0148
Publication history: 
Received on 22 February 2023; revised on 30 March 2023; accepted on 02 April 2023
 
Abstract: 
COVID and H3N2 influenza instances are on ascent in India. Both COVID-19 and H3N2 are the infectious viruses. They promulgate through droplets. COVID is transmitted by SARs –Cov2 virus and H3N2 acquired by Influenza A sub type. Contrast to H3N2, COVID 19 cause more serious and symptoms can take longer than flu symptoms. The COVID-19 not only poses a serious threat to the health of people worldwide but also affects the global economy.

H3N2 is a variety of influenza virus that has been present among humans since the late 1960s. It is often called the "Hong Kong flu" due to its roots in Asia. Viruses that normally disperse in pigs are “swine influenza viruses". H3N2 is a subtype of the viral genus Influenza Virus A, which is a major cause of current respiratory illness. The H3N2 virus is a non-human influenza virus that normally circulates in pigs and has infected humans with symptoms similar to seasonal flu viruses. Influenza outbreaks have caused widespread illness to humans many times throughout history. In 1968 an avian reasserting virus of the H3N2 subtype was introduced into the human population that caused a global pandemic associated with more than one million deaths world-wide. About half of all inpatient severe acute respiratory infections.H3N2 hospitalized patients suffer from fever, cough, breathlessness and wheezing. Few patients needed oxygen and ICU care. Despite significant advancement in vaccine and virus research, influenza continues to be a major public health concern.
 
Keywords: 
Swine influenza viruses; Hemagglutinin (H); Neuraminidase (N); Poly-N-acetyl-lactosamine (poly-LacNAc) chains
 
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