Innovative approaches to risk management in clinical research: Balancing ethical standards, regulatory compliance, and intellectual property concerns

Anita Jumai Ehidiamen * and Olajumoke Omolayo Oladapo

Independent Researcher, Texas, USA.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(01), 349–363.
Article DOI: 10.30574/wjbphs.2024.20.1.0791
Publication history: 
Received on 05 September 2024; revised on 13 October 2024; accepted on 15 October 2024
 
Abstract: 
This study explores innovative approaches to risk management in clinical research, focusing on the intricate balance between ethical standards, regulatory compliance, and intellectual property (IP) concerns. As clinical trials become increasingly complex and globalized, managing risks effectively while maintaining participant safety and upholding legal and ethical principles has become paramount. The study adopts a comprehensive review of emerging technologies, such as artificial intelligence (AI), machine learning (ML), blockchain, and big data analytics, to assess their role in transforming risk management strategies. Key findings reveal that AI and predictive analytics significantly enhance real-time monitoring and the early identification of risks, while adaptive trial designs offer flexibility in managing unforeseen challenges during trials. Blockchain technology improves transparency and data integrity, ensuring secure and verifiable data transactions. However, the intersection of IP protections and equitable access to treatments presents ongoing ethical challenges, particularly in low-income regions. The study concludes that while technological innovations provide robust tools for mitigating risks, a balanced approach to regulatory frameworks and IP protections is essential. The study recommends increased collaboration between regulatory bodies, research institutions, and technology providers to harmonize global regulatory standards, ensuring both innovation and accessibility. Furthermore, it advocates for more flexible IP frameworks that address the tension between protecting innovations and ensuring equitable access to life-saving treatments.
 
Keywords: 
Risk Management; Clinical Research; Regulatory Compliance; Intellectual Property; Artificial Intelligence; Blockchain
 
Full text article in PDF: