A mini-review on influence of physical exercise in remodeling the immune mechanism

Anjali Saxena 1, *, Ankita Dua 3, Mohit Kumar 2, Alivia Roy 1 and Aeshna Nigam 3

1 Department of Zoology, Bhaskaracharya college of Applied Sciences, University of Delhi, New Delhi, India.
2 Department of Physical Education, Bhaskaracharya college of Applied Sciences, University of Delhi, New Delhi, India.
3 Department of Zoology, Shivaji College, University of Delhi, New Delhi, India.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(02), 349–358 .
Article DOI: 10.30574/wjbphs.2024.18.2.0264
 
Publication history: 
Received on 30 March 2024; revised on 08 May 2024; accepted on 11 May 2024
 
Abstract: 
Exercising on a regular basis has been associated with delay in onset of many lifestyle disorders and chronic conditions. Different types of exercise have varied effects on our innate immune cells, both positively and negatively. Low-intensity exercises like yoga or brisk walking, medium-intensity exercises like swimming or cycling, and long-term high-intensity exercises like playing sports like volleyball or working out in the gym are some examples. The immune system's function is impacted differently by exercise training depending on the type, duration, intensity, and other factors. Exercise training is a double-edged sword that helps the body's immune system by changing the immune cells' post-exercise reaction mechanisms. Regular physical exercise is one of the lifestyle adjustments aimed at minimizing morbidity and mortality associated with contemporary illnesses such as obesity, diabetes, cardiovascular disease, and cancer. Regular leisure exercise training is regarded to be beneficial, but extreme exercise, such as that performed by professional athletes, is thought to have possibly detrimental consequences. This review summarizes current information in the field of exercise-associated alterations of infection susceptibility and indicates knowledge gaps for further investigation. It highlights that long term effects of physical activity shows a positive association with longevity and exercise.
 
Keywords: 
Physical activity; Immunity; Infections; Immuno-suppressions; Exercise training intensity
 
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