1 Department of Microbiology and Immunology, Midwestern University, Downers Grove, IL, USA.
2 Department of Chemistry, American University, Washington, D.C., USA.
Received on 23 July 2022; revised on 03 September 2022; accepted on 05 September 2022
The potential of statins as antimicrobials has been recognized for more than a decade; unfortunately, minimal progress in exploring this promise. This mini review highlights the structure of statins and their relevance as antimicrobial co-drug. The current information on the inhibition mechanism of statins on bacterial, fungal, viral, and biofilms is also described.
Fungi 1; Sar-CoV-2 2; Antimicrobial resistance 3; Lactone 4; Biofilm 5; Cholesterol 6
Get Your e Certificate of Publication using below link
Preview Article PDF
Balbina J Plotkin, Alexis Borrelli, Matthew Erbst, Victoria Zheng, Monika I Konaklieva, Nicholas Schileru and Ira M Sigar. Multifunctionality of statins as antimicrobials.World Journal of Biology Pharmacy and Health Sciences, 2022, 11(03), 001–012. Article DOI: https://doi.org/10.30574/wjbphs.2022.11.3.0114