Neonatal severe haemophilia: A case report
Department of neonatology, Children's hospital of Rabat, Faculty of medicine and pharmacy, University Mohammed V, Rabat, Morocco.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 14(01), 165–167.
Article DOI: 10.30574/wjbphs.2023.14.1.0186
Publication history:
Received on 08 March 2023; revised on 17 April 2023; accepted on 20 April 2023
Abstract:
Hemophilia A is an inherited bleeding disorder caused by deficiency of coagulation factor VIII. It is transmitted in an X-linked recessive pattern from female carriers to male children.
We report the observation of a severe hemophilia A in a male newborn with a history of hemophilia in the siblings who present hemarthrosis of the left elbow. The diagnosis was suspected and confirmed through biologic investigations and imaging. Therefore, patient was put under factor VIII with good evolution.
It is a congenital hemorrhagic disease related to deficiency in anti-hemophilic factor. The severity of the bleeding syndrome is correlated to the factor level. There are three varieties of hemophilia: severe, moderate and minor. The main complications are hemarthrosis, hematomas of variable location and externalized hemorrhages. A favorable prognosis depends on rapid diagnosis, monitoring and immediate medical treatment.
Diagnosis of hemophilia A should be rule out in all male newborns with a family history of hemophilia, and suspected in the presence of cord bleeding at birth or during circumcision.
Keywords:
Hemophilia; Neonate; Factor VIII; Hemarthrosis
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0