Optimization and evaluation of bilayer tablet of probenecid

Gopal Gajanan Wagh *, Vinay Mahajan, Ramakant Sharma and Revathi A. Gupta

Institute of Pharmacy, Dr. A.P.J. Abdul Kalam University, Indore, India.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(01), 388–398.
Article DOI: 10.30574/wjbphs.2024.18.1.0226
Publication history: 
Received on 08 March 2024; revised on 24 April 2024; accepted on 25 April 2024
 
Abstract: 
The main objective of my research work is to develop a bilayer tablet of Probenecid, in which one layer is immediate layer for immediate action and second layer is the sustain release layer for maintaining the dose of the drug. Probenecid is frequently administered up to 3 times in a day. So, the reducing dosing frequency by sustained release tablet.
 
Keywords: 
Sustained; Immediate; Probenecid; Optimizing; Frequency.
 
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