An overview of diverticular pathophysiology and its treatment

John Staines Mark *, Sakthi Sundaram Subramaniyam, Pavithra Jaipal, Shila Gunasekaran and Maheswaran Ponnusamy

Department of Pharmacology, Nandha College of Pharmacy, Erode, Tamil Nadu, India. – 638052.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2022, 12(02), 140-155.
Article DOI: 10.30574/wjbphs.2022.12.2.0202
Publication history: 
Received on 14 October 2022; revised on 22 November 2022; accepted on 24 November 2022
 
Abstract: 
Diverticula are protrusions that resemble sacs in the colon's wall. Acute or chronic problems are experienced by 4% of diverticula patients. Diverticulosis development has been linked in large part to the western way of life. Colonic diverticular disease has become more common. Obesity, smoking, and inadequate fibre consumption are risk factors for the illness. Most of the time, surgery is not necessary to treat this; however, if the bleeding is significant, angiography and endovascular intervention may be helpful. Ureteral catheters should be considered when a patient has undergone radiation therapy, resurgery, or preoperative imaging reveals an abnormal anatomy. Oral antibiotics can help prevent surgical site infections after an elective colon resection, according to studies. Using nonabsorbable oral antibiotics like erythromycin, neomycin, and metronidazole reduces surgical site infections overall.
 
Keywords: 
Diverticula; Risk factors; Lifestyle; Nutrition; Antibiotics
 
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