Pathogenicity islands in bacteria of upper respiratory tract infection

Rawaa B. J. Al Daamee 1, Rana H. Raheema 1, *, Qasim Dawood Yasir Altameemi 2 and Maan M.N. AL-Naqeeb 3

1 Departments of Medical Microbiology, Faculty of Medicine, University of Wasit, Iraq.
2 Departments of Pediatric Faculty of Medicine, University of Wasit, Iraq.
3 College of Biotechnology,Al-Qassim Green University, Iraq.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(02), 016–023
Article DOI: 10.30574/wjbphs.2024.18.2.0219
 
Publication history: 
Received on 15 March 2024; revised on 27 April 2024; accepted on 29 April 2024
 
Abstract: 
Children's upper respiratory tract infections (URTIs)—infections of the upper respiratory tract without symptoms of pneumonia—represent a significant socioeconomic and epidemiological issue. The study of microbial pathogenicity, which is a complex multifactorial process complicated by the coordinated activity of genetic regions linked to virulence and resistance determinants, has accelerated due to increased awareness of infectious diseases in humans caused by microbial pathogens. Pathogenicity islands and resistance islands are essential to the evolution of pathogens and seem to work in tandem during the bacterial infection process. While pathogenicity islands encourage the development of illness,
Additionally, pathogenicity islands are part of a vast array of genomic islands that play a vital role in the transmission of bacterial genes. They encode essential characteristics such as virulence, antibiotic resistance, and other supplementary functions.
 
Keywords: 
Pathogenicity islands; Upper Respiratory Tract Infection; Microbial pathogens
 
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