Phenomenon of microbial pathogenicity as a function of bio-molecules
Department of Biochemistry, University of Colorado, Denver, Colorado, USA.
Review
World Journal of Biology Pharmacy and Health Sciences, 2022, 10(03), 036–042.
Article DOI: 10.30574/wjbphs.2022.10.3.0074
Publication history:
Received on 23 March 2022; revised on 02 May 2022; accepted on 04 May 2022
Abstract:
The bacterial pathogenicity phenomenon is the poly-functional biological potency of germs that are realized by factors (determinants) of pathogenicity (PF) in multi-cellular organism.
Biological functions are responsible for bacterial pathogenicity in a multi-cellular host organism: the adhesive function, the function of invasion and penetration into the cell, the function of evasion of host defense, and the damage function. Factors of pathogenicity are representative bio-molecules possessed different functional activity. The ligand - receptor interaction of bacterial PF and receptors on eukaryotic cells is the basis of specific lesions caused by the pathogen.
Keywords:
Bacterial Pathogenicity; Biological Function; Pathogenicity Islands; Infectious Diseases; Prokaryotic and Eukaryotic Organisms
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