Polymorphism of Insulin-like Growth Factor-1 Receptor (IGF1R/TaqI) Gene in Bali Cattle (Bos javanicus) and Its Relationship to the Performance Traits

Bali cattle (Bos javanicus) are the indigenous beef cattle that able to adapt well in most places in Indonesia. This study was aimed to detect the polymorphism of Insulin-like growth factor-1 receptor (IGF1R) gene with PCR-RFLP analysis. Thirty-one (31) of Bali cows from Klungkung Regency of Bali Province were used for the investigation. Research showed that the IGF1R/TaqI gene was polymorphic as the existance of SNP g.269333G>T (intron 12). Three genotypes of GG (0.87), GT (0.10) and TT (0.03) were obtained from the PCR-RFLP analysis. While, the frequency of G allele was higher than T (0.92 vs 0.08). However, the genetic diversity in the IGF1R/TaqI gene of Bali cattle was low (PIC=0.14) and under the genetic equilibrium (χ2=3.74). In general, the heterozygous animals had the high performance traits but not differ significantly. In conclusion, The IGF1R/TaqI gene has the potency for molecular selection to improve the growth traits of Bali cattle.