The potency of plant antimalarial
Department of pharmacology and toxicology faculty of pharmaceutical sciences Bingham university, Karu, Nasarawa state, Nigeria.
Review
World Journal of Biology Pharmacy and Health Sciences, 2022, 12(01), 190–199.
Article DOI: 10.30574/wjbphs.2022.12.1.0113
Publication history:
Received on 05 August 2022; revised on 25 September 2022; accepted on 27 September 2022
Abstract:
Malaria has remained a major cause of morbidity and mortality in all parts of the world. It is associated with high economic burden on the nation, high prevalence of mortality in children, pregnant women and non-immune individuals, thus malaria is a global public health problem. This protozoan infection is mainly characterized by fever, pains, loss of appetite and anaemia, researchers had discovered potent antimalarial drugs mainly from plant sources in order to overcome resistance of antimalarials, vectors, inability to develop malarial vaccines and also toxic effects of conventional antimalarial drugs. Antimalarials obtained from plants have significant roles in drug discovery and development for the treatment of fever, pains, inflammation as well as Plasmodium falciparum infection, therefore this review focuses on the analgesics, antipyretics and anti-inflammatory activities as well as antiplasmodial activities of plants.
Keywords:
Malaria; Potency; Plant antimalarials; Analgesics; Antipyretics; Anti-inflammatories
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