Predictive factors of suicidal behaviors in borderline personality disorder post-discharge: A comprehensive review
1 Vinnytsia National Pirogov Medical University, Vinnytsia Oblast, Ukraine.
2 Manhattan Psychiatry Center New York.
3 General Directorate of Health Affairs, Najran, Saudi Arabia.
4 All Saints University school of medicine, Saint Vincent and the Grenadines.
5 Purdue University Global, School of Business and Information Technology, Indiana, USA.
6 University of Benin, Benin, Nigeria.
7 Celerion Inc, Texas, USA.
8 Windsor university school of medicine, Basseterre, Saint Kitts and Nevis
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 19(02), 268–283.
Article DOI: 10.30574/wjbphs.2024.19.2.0528
Publication history:
Received on 04 July 2024; revised on 11 August 2024; accepted on 14 August 2024
Abstract:
Borderline Personality Disorder (BPD) is a psychiatric condition associated with a significantly elevated risk of suicidal behaviors, particularly during the post-discharge period following inpatient psychiatric care. This review synthesized recent research on the predictive factors of suicidal behaviors in BPD patients, encompassing clinical symptoms, comorbid psychiatric disorders, psychosocial influences, neurobiological markers, and environmental and systemic factors. Clinical variables such as the severity of BPD symptoms, identity disturbance, and history of suicidal behaviors are identified as robust predictors. Psychosocial factors, including interpersonal relationships, social support, and coping mechanisms, further modulate suicide risk. Emerging neurobiological research highlights the role of brain abnormalities, genetic predispositions, and neuroendocrine dysregulation in influencing suicidal behaviors. Additionally, the review emphasizes the importance of addressing environmental and systemic factors, such as access to mental health services and continuity of care, to reduce suicide risk in this vulnerable population. The integration of multiple predictive factors into comprehensive risk assessment tools and the development of personalized intervention strategies are critical for enhancing clinical practice and improving patient outcomes.
Keywords:
Borderline Personality Disorder; Suicidal behaviors; Post-discharge risk; Predictive factors; Neurobiological markers
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0