Prevalence and factors associated to transfusion adverse reactions at the Sourou Sanou University Hospital of Bobo-Dioulasso between January and December 2019
1 Ministry of Health and Public Hygiene, Ouagadougou, Burkina Faso.
2 Joseph KI-ZERBO University of Ouagadougou, Burkina Faso.
3 National Blood Transfusion Centre, Ouagadougou, Burkina Faso.
4 Institute for Interdisciplinary Training and Research in Health and Education Sciences (IFRISSE).
5 Centre MURAZ/National Institute of Public Health, Bobo-Dioulasso, Burkina Faso.
6 Institute of Sport Sciences and Human Development (ISSDH), Ouagadougou, Burkina Faso.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 14(03), 016–023.
Article DOI: 10.30574/wjbphs.2023.14.3.0212
Publication history:
Received on 08 April 2023; revised on 01 June 2023; accepted on 03 June 2023
Abstract:
Introduction: Blood transfusions save thousands of lives every day all around the world. They can, however, cause severe adverses reactions in transfused patients, which can be fatal. Our study's goal was to estimate the incidence of transfusion related adverse events and to identify the factors that contribute to the occurrence of transfusion reactions in transfused patients.
Methods: Between January and December 2019, we conducted a cross-sectional study at the clinical departments of Sourou Sanou University Hospital (CHU-SS).
Results: Transfusion responses occurred at a rate of 29.91 per 1000 blood bags transfused, with 39.13% being infectious and 13.04% being allergic. Transfusion reactions were 3.54 times (p = 0.05) and 4.16 times (p = 0.004) more likely if the blood transfusion lasted less than 30 minutes or more than 60 minutes, respectively, compared to 30 to 60 minutes. When compared to transfusion of up to two blood bags, transfusion of three to four blood bags and more than four blood bags increased the risk of transfusion adverse reaction by 1.67 times (p = 0.032) and 2.17 times (p = 0.049), respectively.
Conclusion: Our research has revealed the prevalence and risk factors for transfusion adverses reactions. The introduction of prevention techniques would increase transfusion safety.
Keywords:
Associated factors; Transfusion reactions; CHU-SS; Bobo-Dioulasso
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0