The profile of cervical dysplasia and cervical cancer of patients at MRCCC siloam Hospital Semanggi
1 Medical Faculty, Universitas Kristen Indonesia, Jakarta Indonesia.
2 MRCCC Siloam Hospital Semanggi, Indonesia.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 044-055.
Article DOI: 10.30574/wjbphs.2023.13.1.0263
Publication history:
Received on 08 November 2022; revised on 21 December 2022; accepted on 24 December 2022
Abstract:
Cervical cancer is one of the most common cancers found in Indonesia however it has not yet been properly resolved. Anatomical pathology archive data of histopathological features from cervical dysplasia and cancer lesions of 108 patients, who met the inclusion criteria, at MRCCC Siloam Hospital Semanggi in 2018 to 2020 are collected. This study is using retrospective design. Techniques were used to get the specimens are 66.7% cervical biopsy and 33.3% hysterectomy. There were 21.3%, 40.7% and 38% patients who were diagnosed with cervical dysplasia or cancer respectively in 2018, 2019 and 2020. Most of them who were diagnosed with cervical dyplasia lesions at the age of 20-29 and those with cervical cancer were at the age of 40-49. HPV DNA examination results show 21.3% were positive for High-Risk HPV types and 1.9% had positive results for a combination of High-Risk and Low-Risk types, which HPV type 16 was found the most. Histopathological examination intepretations of patients with dyplasia shows 61.9% had LSIL and 38.1% had HSIL. Those with cervical cancer shows 65.2% had squamous cell carcinoma and 34.8% had adenocarcinoma. Risk factors have important role in cervical dysplasia that can develop into cervical cancer, especially HPV infection. Routine test and histopathological examination are the only way to find out the possibility of cervical dysplasia/precancerous lesion or cancer so patients could receive prompt and appropriate management sooner.
Keywords:
Histopathology; Cervical cancer; Cervical dysplasia; HPV
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