A review of compounds derivatives with antimicrobial activities

Thangabalan Boovizhikannan * and Ramya Nethakara Mahesh

Department of Pharmaceutical Analysis, Sri Venkateswara college of Pharmacy, RVS Nagar, Tirupati Rd, Chittoor, Andhra Pradesh 517 127, India.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 224-237.
Article DOI: 10.30574/wjbphs.2023.13.1.0019
Publication history: 
Received on 27 November 2022; revised on 07 January 2023; accepted on 10 January 2023
 
Abstract: 
Antimicrobial resistance represents a serious threat to human health across the globe. The cost of bringing a new antibiotic from discovery to market is high and return on investment is low. Furthermore, the development of new antibiotics has slowed dramatically since the 1950s’ golden age of discovery. Medicinal compounds synthesis produce a variety of bioactive compounds that could be used to build a new way for the future discovery pipeline. While many studies have focused on specific aspects of synthetic compounds with antibacterial properties, a comprehensive review of the antibacterial potential of compounds has never before been attempted. This review aims to evaluate reports on some derivatives with significant antimicrobial activities.
 
Keywords: 
Antimicrobial activities; Medicinal compounds; Synthetic derivatives; Heterocyclic compounds
 
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