Samartha Institute of Pharmacy, Belhe, Pune, Maharashtra, India.
World Journal of Biology Pharmacy and Health Sciences, 2026, 26(01), 286–291
Article DOI: 10.30574/wjbphs.2026.26.1.0230
Received on 21 March 2026; revised on 28 April 2026; accepted on 30 April 2026
CRISPR-Cas9 is a revolutionary genome editing tool transforming pharmaceutical sciences. It enables precise modification of DNA sequences and has applications in genetic disorders, cancer ,and infectious diseases. This review provides detailed insights into its mechanism, applications, challenges, and future scope.CRISPR-Cas9 is a revolutionary genome editing tool transforming pharmaceutical sciences. CRISPR technology's ability to precisely and flexibly edit genes has opened up new ways to find, validate, and develop drug targets. Also, it has made way for personalized gene therapies, precise gene editing, and advanced screening techniques, all of which hold great promise for treating a wide range of diseases. In this article, we look at the latest research and clinical trials that show how CRISPR could be used to treat genetic diseases, cancer, infectious diseases, and other hard-to-treat conditions. However, ethical issues and problems with regulations are also discussed in relation to CRISPR-based therapies, which shows how important it is to use them safely and responsibly. As CRISPR continues to change how drugs are made and used, this review shines a light on the amazing things that have been done and what the future might hold in this rapidly changing field.
CRISPR-Cas9; Gene Therapy; Genome Editing; Personalized Medicine; Drug Delivery; Biotechnology
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Vaishnavi Dattatray Shimpi, Prachi Nandakumar Padwal and Sancheti Santaram Rode. A review on: CRISPR-based gene therapy in pharmacy: A revolutionary approach in modern therapeutics. World Journal of Biology Pharmacy and Health Sciences, 2026, 26(01), 286–291. Article DOI: https://doi.org/10.30574/wjbphs.2026.26.1.0230