A review on immunization of DNA vaccine
Department of Pharmaceutics, Senghundhar College of Pharmacy, Kumaramangalam, Tiruchengode-637205 Namakkal.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(03), 658-669.
Article DOI: 10.30574/wjbphs.2024.20.3.1075
Publication history:
Received on 16 November 2024; revised on 26 December 2024; accepted on 28 December 2024
Abstract:
DNA vaccines represent a cutting-edge approach to immunization by utilizing genetic material to induce an immune response. Unlike traditional vaccines that use weakened or in activated pathogens, DNA vaccines deliver a plasmid containing genes encoding specific antigens into the host cells. These cells then produce the antigens, stimulating a protective immune response. This method offers several advantages, including rapid development, ease of production, and the ability to target a wide range of diseases. DNA vaccines have shown promise in preclinical and clinical trials for various infectious diseases, cancer, and genetic disorders. Ongoing research focuses on optimizing delivery systems, improving efficacy, and ensuring safety to enhance their potential as a transformative tool in modern medicine. Electroporation and nanoparticle-based systems, to improve the effectiveness and safety of DNA vaccines
Keywords:
DNA vaccine; Vaccine preparation; Delivery method; Immunization
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0