A review of medicines with sustained release
Malla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dhulapally, Post Komapally, Medchal Mandal, Secunderabad-500 100, India.
Review
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(03), 221–233.
Article DOI: 10.30574/wjbphs.2023.13.3.0141
Publication history:
Received on 16 February 2023; revised on 24 March 2023; accepted on 27 March 2023
Abstract:
Sustained-release matrix tablets allow for continuous drug release while also optimizing a drug's biologic, pharmacokinetic, and pharmacodynamic properties for maximum therapeutic efficacy. The matrix regulates the rate at which the drug is released. Because it facilitates prolonged release, the major excipient in the formulation is a release retardant. The technology may promote patient compliance and efficiently treat chronic illnesses by decreasing the overall dosage and dosing schedule. The drug is supplied in this system via diffusion- and dissolution-controlled methods. The primary goal of this analysis is to provide comprehensive information on the sustained release system and to discuss the many selection criteria for medicines used in medication administration system
Keywords:
Sustained; Matrix; Tablets; Dissolution; Diffusion; Drug
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0