A review on the wet granulation technique and its modules

Wet granulation is a processes that involves adding a liquid to a powder to create granule of a desired size and shape. Its used in many fields, including pharmaceutical, neutraceutical and zootechnics to improve the flowbility, compressibility, and dosage of powders. Their are different technique of wet granulation.
Low shear wet granulation, which is a form of wet granulation, is an important unit operation in the pharmaceutical, detergent and food industries. The granulation mechanism for wet granulation include wetting and nucleation, consolidation and growth and attrition and breakage. High shear wet granulation is considered a complicated and multivariate pharmaceutical process that is influenced by large number of variable derived from equipment, formulation, and processing. Fluid bed granulation is an important process within a drug product manufacturing framework since it sets the properties of the intermediate product the make the final drug product.