Serum in Behcet's disease determination of leptin and vitamin D levels
1 Sivas Cumhuriyet University, Faculty of Science, Department of Biology SİVAS.
2 Ahmet Karadag, Sivas Cumhuriyet University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, SIVAS/TURKEY.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2020, 04(02), 026-031.
Article DOI: 10.30574/wjbphs.2020.4.2.0089
Publication history:
Received on 25 October 2020; revised on 03 November 2020; accepted on 04 November 2020
Abstract:
The aim of this study was to measure serum leptin and vitamin D levels in remission in Behcet's disease (BD) and to investigate the relationship between leptin and vitamin D levels with neutrophil / lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR). This study was conducted in 20 healthy volunteers and 27 BH who were in remission. The age, sex, and body mass index values (BMI) of both groups were recorded. Venous blood samples were taken from both groups at the end of 12 h fasting. Serum leptin, vit-D, high-sensitivity C-reactive protein (hsCRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC), neutrophil, lymphocyte and platelet counts were measured from the obtained sera according to the kit protocols. There was no statistically significant difference between the groups in terms of hsCRP, ESR, WBC, leptin, vit-D and NLR and PLR values (p> 0.05). Correlation of leptin levels with NLR and PLR values in both groups were not statistically significant (p>0.05). The results showed that there was no relationship between the measured values and the course of the diseaseBD
Keywords:
Behcet's disease; Leptin; 25-hydroxyvitamin D
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