1 Senior Resident, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
2 Post Graduate, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
3 Professor, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
4 Director Professor, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
5 Senior Resident, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
6 Senior Resident, Department of Obstetrics and Gynaecology, MAMC and associated Lok Nayak Hospital, Delhi.
World Journal of Biology Pharmacy and Health Sciences, 2025, 23(02), 126–132
Article DOI: 10.30574/wjbphs.2025.23.2.0734
Received on 25 June 2025; revised on 02 August; accepted on 05 August 2025
Introduction: Abruption is a common cause of Antepartum Hemorrhage and complicates 0.4-1% pregnancies overall. Severe abruption is defined as evidence of maternal shock or coagulation defects, uterine tetany and intrauterine death of fetus according to the Page classification.
Objective: To study maternal and perinatal outcomes in patients with severe abruption
Methods: All pregnant women with severe abruption, grade 3 of Page classification were included. Complete evaluation was done with presenting complaints, obstetric history, past history, associated obstetric co-morbidites, obstetrical examination and relevant investigations were done. Maternal and perinatal outcomes were observed and analysed.
Results: Among 8600 pregnant women admitted, the incidence of abruption was 1.8% (n=158), with 23 cases being classified as severe. Half of the patients (52%) had abruption at early preterm gestation (<34 weeks). Most common associated risk factor was presence of pre-eclampsia in 65% patients. More than half (56.5%) had vaginal delivery. Major maternal complications observed included PPH in all patients, DIC in 22% patients and AKI in 30.4% patients. Perinatal mortality was 78.2% and 26% required NICU admission.
Conclusion: Abruption is one of the major causes of maternal and fetal morbidity and mortality. Early identification and timely termination leads to reduction in maternal complications, but still has a poor perinatal outcome. The aim should be early termination of pregnancy.
Abruption; AKI; DIC; PPH
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Rachita Garg, Madiha Khan, Preeti Singh, Latika Sahu, Nasrin Fatima and Pallavi Pathak. Severe abruption: Maternal and Perinatal Outcomes. World Journal of Biology Pharmacy and Health Sciences, 2025, 23(02), 126-132. Article DOI: https://doi.org/10.30574/wjbphs.2025.23.2.0734.