Study of antimicrobial activity of novel Isatin derivatives

Sravanthi Chirra 1, *, S Neelufar Shama 2, D Pranitha 3, Ch Madhav Reddy 1 and Venkateshwar Rao Jupally 4

1 Department of pharmaceutical chemistry, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad,Telangana, India-501506.
2 Department of Pharmacognosy, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad, Telangana, India-501506.
3 Department of pharmaceutics, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad, Telangana, India-501506.
4 Department of pharmaceutical chemistry, Talla Padmavathi College of Pharmacy, Orus, Warangal, India-506002.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 039-043.
Article DOI: 10.30574/wjbphs.2023.13.1.0285
Publication history: 
Received on 03 November 2022; revised on 29 December 2022; accepted on 31 December 2022
 
Abstract: 
Objective: The aim of this study to synthesize, characterize and screen some new isatin derivatives for their antimicrobial activities.
Method: A library of isatin derivatives were synthesized, structures of newly synthesized compounds were deduced based on spectral data and elemental analysis.
Results: Antibacterial activity was screened against gram positive and gram negative bacterial strains.
Conclusion: The novel isatin derivatives produce significant antimicrobial activities.
 
Keywords: 
Isatin; Antibacterial; Antifungal; Analgesic; Anticonvulsant activity
 
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