A systematic review of therapeutic trends in preterm Labour

Premature birth, occurring before 37 weeks of pregnancy, is a significant health concern. It can lead to various complications for both the mother and the baby, contributing to neonatal morbidity and mortality. The risk of long-term neurological and developmental disorders increases with the degree of prematurity. There are several risk factors for preterm labour and premature birth such as antepartum heamorrhage, Urinary tract infections (UTI), certain vaginal infections etc. Certain lifestyle and environmental factors including: Late or no health care during pregnancy, Smoking, Drinking alcohol, Using illegal drugs etc. Premature birth can result in various health issues for preemie babies. Common health conditions include respiratory distress syndrome, intraventricular hemorrhage, patent ductus arteriosus (heart issues), and necrotizing enterocolitis etc. Symptoms of Preterm Labor include Contractions, Cramping or pain in the lower abdomen, fluid leaking from the vagina, increase in vaginal discharge, increased pressure in the vagina or the pelvis. Tocolytics are the drug of choice to delay the uterine contractions for atleast 48 hours.