Thin layer chromatographic investigation of antibiotics residues in edible poultry tissues in Bangladesh

Md. Shafiqul Islam *, Md. Rakibul Hasan, Md. Shakil Islam

Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2021, 05(03), 024-032.
Article DOI: 10.30574/wjbphs.2021.5.3.0019
Publication history: 
Received on 27 January 2021; revised on 26 February 2021; accepted on 01 March 2021
 
Abstract: 
Majority of the people in Bangladesh are still not aware about the health hazards of antibiotic residues. In this perspective, a survey was undertaken at five different poultry farms in the Dinajpur district. One hundred liver, one hundred thigh muscle and one hundred breast muscle samples were collected from different farms & market places and evaluated by TLC method. A very negligible number of samples were found positive for antibiotics residues. Out of one hundred liver, one hundred thigh muscle and one hundred breast muscle samples respectively; only two liver, two breast muscle and two thigh muscle samples were found positive for amoxicillin antibiotic; five liver, three breast muscle and three thigh muscle samples were found positive for ciprofloxacin; three liver, two breast muscle and two thigh muscle samples were found positive for cephalexin; two liver, two breast muscle and two thigh muscle samples were found positive for enrofloxacin; four liver, two breast muscle and two thigh muscle samples were found positive for oxytetracycline. Gentamicin and neomycin were found negative for any samples. Further investigation was done in indoor discriminate and indiscriminate use of antibiotics (ciprofloxacin and oxytetracycline) in broilers. Liver, thigh muscle and breast muscle samples were collected and evaluated by TLC method. Therefore, poultry treated with antibiotics are required for specific withdrawal period until all residues are depleted to safe levels before human consumption. This research project provides idea that Bangladeshi poultry products are free of antibiotics residues in north area (Dinajpur District) of Bangladesh.
 
Keywords: 
Antibiotic residues; TLC; Oxytetracycline; Ciprofloxacin
 
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