Treating developmental dyslexia using transcranial stimulation combined with a reading stimulation program: A pilot study

Isabela Ciola de Castro 1, *, Mauro Muszkat 2, Vânia Carvalho Lima 1, Sueli Rizzutti 2 and Clara Brandão de Ávila 1

1 Department of speech-language and hearing sciences - Paulista School of Medicine- Federal University of São Paulo, Address: Rua Botucatu, 802 - Vila Clementino- 04023-062 - São Paulo - Brazil.
2 Department of Psychobiology - Federal University of São Paulo, R. Napoleão de Barros, 925, 04021002 - São Paulo - Brazil.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2021, 07(03), 080–088.
Article DOI: 10.30574/wjbphs.2021.7.3.0105
Publication history: 
Received on 19 August 2021; revised on 25 September 2021; accepted on 27 September 2021
 
Abstract: 
Objective: Evaluate the effect of transcranial direct current stimulation (tDCS) combined with reading therapy on the performance of reading tasks in a serie of cases of children and adolescents with developmental dyslexia (DD).
Method: (IRB/UNIFESP number:1281/2017). Four dyslexic students (two children and two adolescents) were evaluated with regards to rate and accuracy of reading fluency on three occasions: pre-intervention as well as one and six months after intervention. The intervention consisted of five consecutive sessions of active tDCS (1 mA for 20 minutes), followed by a two-day interval and another five sessions of tDCS combined with cognitive skills stimulation of phonological processing and decoding of words. Anodal tDCS was administered over the left parieto-occipital cortex, with the cathode placed over contralateral deltoid muscle. Each session was preceded by execution of semantic-lexical and phonological evocation tasks. Data were analyzed using Friedman test and JT method for analysis of clinical significance and the reliable change index.
Results: Improvements were found in text reading rate and accuracy and word accuracy at the one-month and six-month evaluation. A significant increase was found in correct reading of words and pseudowords six months after intervention. Most of the improvements were reliable, with clinical significance in some cases. Conclusion: Transcranial direct current stimulation combined with a reading stimulation program proved effective at improving reading skills in these participants.
 
Keywords: 
Dyslexia; Transcranial Direct Current Stimulation; Reading; Longitudinal Study
 
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