Verification of analytical performance of glycosuria assay on the Abbott Architect® analyzer: Experience of the Biochemistry Laboratory, Mohammed VI University Hospital of Oujda

The aim of our study was to evaluate the analytical performance of the glycosuria assay method using the ARCHITECT c Systems automated analyzer in the biochemistry laboratory of the Mohammed VI University Hospital in Oujda. 

Glycosuria, defined as the presence of glucose in urine, is a key biomarker in the diagnosis and monitoring of diabetes mellitus, reflecting disturbances in glucose metabolism.

We conducted a performance study of the ARCHITECT c Systems analyzer, focusing on repeatability and reproducibility, in accordance with the COFRAC GTA 04 accreditation technical guide, which aligns with the quality requirements of ISO 15189 standards.

The results of our study demonstrate satisfactory repeatability for two levels of glycosuria (Low, High), with CV1 = 1.70%, CV2 = 1.68%, Similarly, reproducibility was satisfactory with coefficients of variation (CV) for the same levels, showing CV1 = 3.66%, CV2 = 1.55%.

The reliability of our glycosuria assay results is confirmed by the satisfactory analytical performance obtained, which meets the quality standards required for clinical laboratory diagnostics. These findings underline the robustness of the ARCHITECT c Systems analyzer and its compliance with ISO 15189 accreditation criteria.