1 Assistant Professor, Department of Pharmaceutical Chemistry, SCES’s Indira College of Pharmacy, Tathawade, Pune 411033.
2 Professor and Head, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai, Tamil Nadu.
World Journal of Biology Pharmacy and Health Sciences, 2025, 24(02), 329-342
Article DOI: 10.30574/wjbphs.2025.24.2.0972
Received on 01 October 2025; revised on 08 November 2025; accepted on 10 November 2025
As a useful model in cancer research, zebrafish (Danio rerio) have made substantial contributions to precision medicine, drug testing, and discovery. They are the perfect system for in vivo research of cancer progression and therapy responses because of their fast growth, genetic resemblance to humans, and transparent embryos. This article examines the use of zebrafish in pharmacogenomics, personalised medicine development, and high-throughput cancer medication screening. We also go over the benefits and drawbacks of using zebrafish models in oncological research as well as its possible applications in precision medicine in the future.
Zebrafish Model; Cancer Research; Drug Discovery; Precision Medicine; Pharmacogenomics
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Rutuja Kamble and Krishnan Karthickeyan. Zebrafish (Danio rerio) in cancer research: A revolutionary model for drug testing, discovery, and precision medicine. World Journal of Biology Pharmacy and Health Sciences, 2025, 24(02), 329-342. Article DOI: https://doi.org/10.30574/wjbphs.2025.24.2.0972.