Comparative assessment of analgesic activity between whole plant and parts of Azadirachta Indica
1 Birbhum Pharmacy School, Dubrajpur, Birbhum, West Bengal, India.
2 Gupta College of Technological Sciences, Asansol, West Bengal, India.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 13(01), 401-412.
Article DOI: 10.30574/wjbphs.2023.13.1.0235
Publication history:
Received on 30 October 2022; revised on 06 December 2022; accepted on 09 December 2022
Abstract:
Azadirachta Indica is a most common medicinal plant which is use for Antibacterial, Antifungal, Antiulcer, Antiviral, Analgesic, sedative properties.
Objective: The aim of the study was Comparative Assessment of Analgesic Activity between whole plant and parts of Azadirachta Indica in experimental animal model.
Methods: The extracts were prepared by maceration method. Analgesic activity was assessed by tail flick method and hot plate method (for central action) and acetic acid-induced writhing test (for peripheral action).
Results: Seed extract, whole plant extract and aspirin showed significant analgesic activity, both central and peripheral, as compared to control (p< 0.01). Although Whole plant extract at dose of 500 mg/kg showed better activity than 250 mg/kg (p <0.05).
Keywords:
Analgesic; Azadirachta Indica; Maceration; Tail flick; Writhing
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