Neonatal Rhabdomyosarcoma: About a new observation
National Reference Center for Neonatology, Children's Hospital Chu Rabat, Research team in health and nutrition of the mother-child couple. Faculty of Medicine and Pharmacy. Mohamed V University Rabat, Morocco.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 14(01), 153–157.
Article DOI: 10.30574/wjbphs.2023.14.1.0176
Publication history:
Received on 06 March 2023; revised on 15 April 2023; accepted on 18 April 2023
Abstract:
Rhabdomyosarcoma is a cancer that develops from so-called "soft" tissue. In neonates, as well as in older children, rhabdomyosarcoma is the most common malignant soft tissue tumor. Malignant mesenchymal tumors are, after neuroblastoma, the second most common type of cancer in the newborn.
Our case is a female neonate, 2nd of 2 siblings, full term, eutrophic, admitted at H4 of life with respiratory distress rated 2/10 according to the silverman score with left choanal atresia. The oral examination revealed several solid pinkish masses and the cervico-facial CT scan showed an oval retro pharyngeal collection associated with infiltration of the superficial and deep left neck and upper mediastinum spaces.
The histopathological study found a morphological and immunohistochemical aspect of an embryonal rhabdomyosarcoma.
Rhabdomyosarcoma is rare in the neonatal period, it is located mainly in the limbs, genitourinary tract and head and neck region. As was the case with our newborn who presented with an oropharyngeal location.
Their diagnosis can be difficult and requires the advice of an expert anatomopathologist. Their management must be multidisciplinary.
Keywords:
Rhabdomyosarcoma; In-newborn; Tumors; Embryonic; Neonatal
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0