Formulation and evaluation of mouthwash using guava leaves for aphthous ulcer treatment

Mouth ulcers are small sores that form on your gums, lips, tongue, inner cheeks or roof of your mouth. Lots of different things can cause them, including minor injuries, hormonal changes, biting your cheeks or tongue, lack of sleep, eating acidic food, emotional stress and oral hygiene. Many mouth ulcers go away on their own. Others may require treatment .Generally, for prevention of Mouth ulcers/canker sores the different types of formulations are used, such as pastes, gels, tablets, paints and mouthwashes. Psidium guajava Linn. (guava) is used not only as food but also as folk medicine in subtropical areas around the world because of its pharmacologic activities.It is demonstrated that the pharmacological ability of this plant to show antioxidant, hepatoprotective, anti allergy, antimicrobial, antispasmodic, cardioactive, antidiabetic, anti inflammatory and antinociceptive activities. Guava leaves mouthwash was effective for aphthous ulcers in terms of reduction of symptoms of pain and faster reduction of ulcer size. further formulating mouthwash which has efficiency to inhibit the growth of the microorganism. This study is an attempt to outline such natural substances, which may be used as effective mouthwashes.