Verification of analytical performance of the aspartate aminotransferase assay on the Abbott Alinity ci®: Experience of the central laboratory Mohammed VI Oujda
1 Central Laboratory, Mohammed VI University Hospital, Oujda, Morocco.
2 Mohammed First University, Faculty of Medicine and Pharmacy of Oujda, Morocco.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2023, 15(03), 037–042.
Article DOI: 10.30574/wjbphs.2023.15.3.0378
Publication history:
Received on 26 July 2023; revised on 07 September 2023; accepted on 09 September 2023
Abstract:
The standard NF EN ISO 15 189 mandates the verification of analytical methods. It involves evaluating an analytical method's effectiveness in accordance with a precisely laid out protocol before comparing it to previously established analytical objectives. Any biologist must be concerned with mastering this approach. In this work, we compare two automats: Alinity ci ® and Architect ci-8200® Abbott, to show the results of the protocol of verification of the method of determination of aspartate aminotransferase (AST). Aspartate aminotransferase is an enzyme found in many tissues, particularly liver and muscle, including heart muscle. Its measurement is particularly useful for diagnosing and monitoring liver disease.
Keywords:
Aspartate aminotransferase; Verification; Repeatability; Reproducibility; Alinity ci®; Architect ci8200®
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0