The impact of prolactin and vitamin D levels as a prognostic markers of female hair loss

Areej Shakeer Jassum, Wafaa Ayad Al-Nuaimy *, Nuha. M. Mousa, Hawraa Aqeel Abdul Munem and Sheereehan A.M. Albyati

Department of biology, College of Science, Al-Muthana University, Iraq.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 17(01), 035–042.
Article DOI: 10.30574/wjbphs.2024.17.1.0513
Publication history: 
Received on 07 November 2023; revised on 06 January 2024; accepted on 08 January 2024
 
Abstract: 
A limited number of case reports seem to point the interaction between thinning hair and a vitamin D deficiency. This research looked at the relationship between prolactin levels and vitamin D levels in women with hair loss. The anterior pituitary gland secretes a polypeptide hormone called prolactin, which has a variety of biological effects, including the capacity to encourage growth and have a proliferative influence on human keratinocytes. Calcium homeostasis is affected by this hormone as a result of deficiency in vitamin D. This study was conducted on 75 patients during the period from November 2019 to March 2021. Serum prolactin and vitamin D levels were measured by chemiluminescence through an immunoassay (automated) and fluorescence Immunoassay (FIA) for vitamin D measurement. Serum prolactin levels were significantly elevated in pregnant women with hair loss compared with healthy controls. Vitamin D and serum prolactin levels had a remarkable positive correlation (r = 0.661, P 0.005). Prolactin and vit. D may play a part in hair loss in women.
 
Keywords: 
Hair loss; Supplementation; 25(OH) vitamin D; Prolactin
 
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