Cytotoxic evaluation of curcumin and quercetin in MCF-7 cell lines
1 Department of Pharmacology, JKK Nataraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India.
2 Chettinad School of Pharmaceutical Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam – 603 103, Tamilnadu, India.
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 17(02), 149–154.
Article DOI: 10.30574/wjbphs.2024.17.2.0048
Publication history:
Received on 26 December 2023; revised on 03 February 2024; accepted on 06 February 2024
Abstract:
Cytotoxic evaluation of Curcumin and Quercetin in MCF-7 cell lines was performed to assess their potential anticancer activity. MCF-7 is a widely used breast cancer cell line, and evaluating the cytotoxic effects of the compounds on these cells can provide valuable information about their potential as an anticancer agent. Curcumin, a naturally occurring compound found in turmeric, has been extensively studied for its potential anticancer properties, including its effects on MCF-7 cell lines. MCF-7 cells are commonly used as a model for studying breast cancer. Quercetin, a flavonoid found in various fruits, vegetables, and plant-based foods, has also been studied for its potential anticancer effects, including its effects on MCF-7 cell lines. The combination of curcumin and quercetin has been investigated for its potential synergistic effects on MCF-7 cell lines, aiming to enhance the anticancer activity of both compounds. The synergistic effects observed in the combination of curcumin and quercetin on MCF-7 cells suggests that the compounds may act through complementary mechanisms, enhancing their individual anticancer activities.
Keywords:
Curcumin; Quercetin; Cytotoxic effects; MCF-7 cells
Full text article in PDF:
Copyright information:
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0